Route 66 in the US: Complete Guide, Itinerary and Visas

by Visagov | March 10, 2026

End of the Road on Route 66

Route 66, known worldwide as the Mother Road, is the ultimate road trip. Spanning nearly 4,000 kilometers (2,448 miles) and connecting East to West, it crosses eight states and offers a perfect snapshot of American culture.

If you're planning this adventure, here's everything you need to know to keep your engine running.

Preparation: Visas and Entry Requirements for the US

Before you start dreaming about neon-lit motels, the most important step is securing your entry into the country. For most international travelers, this means obtaining an ESTA authorization or a tourist visa. Make sure you meet the requirements and have the documentation you need to make the trip.

While you can try to handle it on your own, government forms tend to be rigid — and even a minor mistake can lead to a denial that derails your plans. At Visagov, we specialize in making this process easier: we review your application professionally and transparently so you get your approval stress-free. Processing your visa with us is the first sure stop on your journey.

Logistics: Car, Budget and Weather

When is the best time to travel?

  • Spring and Fall: These are the ideal seasons (May, June, September and October). You'll avoid the extreme desert heat and the snowstorms up north.

  • Summer: Peak season. There'll be more life in the towns, but be ready for temperatures that can exceed 38°C in Arizona and Texas.

Renting a vehicle

The most common approach is to pick up your car in Chicago and drop it off in Los Angeles. Keep in mind that rental companies usually charge a one-way fee for returning the car to a different location. This is an additional cost to factor into your budget.

Estimated budget

This isn't a cheap trip, but it's an adaptable one. Your main expenses will go toward gas (which varies in price by state), accommodation at historic motels and meals at classic diners. It's worth traveling with a flexible budget and always carrying comprehensive travel health insurance, since healthcare costs in the US can be very high.

A Route 66 landscape

State-by-State Itinerary: What to See and Where to Stop

Illinois: The starting point

The route begins in vibrant Chicago. Look for the "Begin Route 66" sign on Adams Street.

  • Don't miss: The restaurant Lou Mitchell's and the Gemini Giant, a 9-meter fiberglass statue in Wilmington.

Missouri: Caves and bridges

Here the road gets more wooded and hilly.

  • Don't miss: Meramec Caverns, caves that once sheltered outlaw Jesse James, and the historic Chain of Rocks bridge over the Mississippi.

Kansas: A nostalgic breath

It's the shortest stretch (only 21 km), but remarkably well preserved.

  • Don't miss: The town of Galena and the famous "Cars on the Route," the gas station that inspired Disney's film Cars.

Oklahoma: The soul of the road

This state has more drivable miles of the original route than any other.

  • Don't miss: The Blue Whale of Catoosa (a kitsch icon perfect for photos) and the Route 66 Museum in Clinton, a must-see for understanding the history of the journey.

Texas: Cattle and Cadillacs

Everything's bigger here. You'll cross the Texas Panhandle.

  • Don't miss: Cadillac Ranch in Amarillo (bring your own spray paint to tag the cars) and the Midpoint Café, which marks the exact halfway point of the route.

New Mexico: Adobe landscapes

The altitude rises and the scenery turns desert-red.

  • Don't miss: The old town of Albuquerque and a short detour to Santa Fe, the oldest state capital in the US, packed with art and Native culture.

A great idea is to grab a margarita at one of the bars or at the Santa Fe Plaza, where you'll also find a lovely artisan market.

An old gas station in Illinois, Route 66 United States

Arizona: The desert in full glory

For many, this is the most spectacular and photogenic stretch.

  • Don't miss: The town of Seligman, birthplace of the movement to save the route, and the legendary Hackberry gas station. And of course, this is the state where you should detour to visit the Grand Canyon.

California: The end of the road

You'll cross the Mojave Desert before reaching the coast.

  • Don't miss: The Santa Monica Pier, where you'll find the "End of the Trail" sign. It's the perfect spot to watch the sunset and celebrate the end of your adventure.

Your Adventure Starts with the Right Paperwork

Driving Route 66 takes thousands of miles behind the wheel — but it also takes clear administrative planning. At Visagov, we make sure your entry into the United States is smooth and free of last-minute surprises.

Not sure whether you need an ESTA or a traditional visa? Talk to us and let us handle the paperwork while you put together your road trip playlist.

Select your document